Endocrine Abstracts

Background: (Pro)renin receptor[(P)RR] is a multi-functioning transmembrane protein which plays key roles in the regulation of tissue renin-angiotensin system (RAS). (P)RR is cleaved by furin to generate soluble (P)RR[s(P)RR], which is secreted into extracellular space. We previously reported that high blood concentration of s(P)RR indicates poor organ prognosis in several diseases. In this way, s(P)RR is expected as a candidate biomarker for reflecting the tissue RAS status, ...

Introduction: TSH-secreting pituitary adenoma (TSHoma) sometimes brings on rare cause of hyperthyroidism because of its excessive TSH secretion. Though the first line of treatment for TSHoma is surgical removal of tumour, hyperthyroidism often causes perioperative thyroid storm. Here, we report a case of GH-TSH pituitary adenoma whose thyrotoxicosis was controlled by 5 days’ octoreotide (OCT) subcutaneous administration before surgery.Case report: A...